Short Research Description
The Quave lab applies the ethnobotanical approach to drug discovery. We examine botanical natural products for anti-virulence activity in treatment of multidrug-resistant bacterial infections. This involves field research to document traditional therapies for skin infections, collection of plants for chemical extraction, and bioassay-guided fractionation strategies to isolate novel drugs. You can check the stats on our work in Google Scholar.
† Awards, honors, or high citations associated with the publication; ‡ Description of my contribution if I am neither first nor last author (per Emory guidelines); ** Students/postdocs/medical residents I have trained, undergraduate researchers are underlined; # Equal contributions.
Published and Accepted Review Articles in Peer Reviewed Journals:
- Salam, A.** and C.L. Quave (2018). Opportunities for plant natural products in infection control. Current Opinion in Microbiology 45: 189-194 [Link]
- Salam, A.** and C.L. Quave. (2018) Targeting virulence in Staphylococcus aureus by chemical inhibition of the accessory gene regulator system in vivo. mSphere 3(1). DOI: 10.1128/mSphere.00500-17 [Link]
- De la Parra, J.** and C.L. Quave. (2017). Ethnophytotechnology: Harnessing the power of ethnobotany with biotechnology. Trends in Biotechnology S0167-7799(17)30170-1. doi: 10.1016/j.tibtech.2017.07.003 [Link]
- Bonchak, J.G.**, S. Thareja, S.C. Chen, C.L. Quave. (2017). Botanical Complementary and Alternative Medicine for Pruritis: A Systematic Review. Current Dermatology Reports 6(4): 248-255 https://doi.org/10.1007/s13671-017-0200-y [Link]
- Quave, C.L. and A.R. Horswill. (2014). Flipping the switch: Tools for detecting small molecule inhibitors of staphylococcal virulence. Frontiers in Microbiology. 5(706):1-10. doi: 10.3389/fmicb.2014.00706 [Link]
- Sõukand, R., C.L. Quave, A. Pieroni, M. Pardo-de-Santayana, J. Tardío, R. Kalle, Ł. Łuczaj, I. Svanberg, V. Kolosova, L. Aceituno-Mata, G. Menendez, I. Kołodziejska-Degórska, E. Pirożnikow, R. Petkevičius, A. Hajdari, B. Mustafa. (2013). Plants used for making recreational tea in Europe: A review based on specific research sites. Journal of Ethnobiology and Ethnomedicine. 9:58. [Link]
- ‡ Contributed to literature review, data analysis, writing and revising the article.
- Quave, C.L., M. Pardo-de-Santayana, and A. Pieroni (2012) Medical ethnobotany in Europe: from field ethnography to a more culturally-sensitive evidence-based CAM? Evidence-Based Complementary and Alternative Medicine. doi:10.1155/2012/156846. [Link]
- Rose, J., C.L. Quave, and G. Islam. (2012) The four-sided triangle of ethics in bioprospecting: Pharmaceutical business, international politics, socio-environmental responsibility and the importance of local stakeholders. Ethnobiology and Conservation.1:3. [Link]
- ‡ Contributed to literature review, writing and revising the article.
- McCullough, I.**, Kucheryavyy**, and C.L. Quave (2012). Immune modulation as a tool in promoting recovery from traumatic brain injury and stroke. Journal of Undergraduate Research and Scholarly Excellence 3 (1): 6-10. [Link]
- Quave, C.L. (1999). Paradise lost? Ethnobotany and its relevance to tropical forest conservation in Amazonia. The Emory Anthropologist: A Journal of Undergraduate Research 4: 24-30.
- Quave, C.L. (October 2017) Green fingers: How much untapped potential do plants have for both discovering and manufacturing drugs? The Medicine Maker magazine. [Link]
- Rose, G. Islam, C.L. Quave (May 7, 2012). Global controversies in bioprospecting. Caros amigos (Brazilian newspaper)
Editorials and Invited Commentaries:
- Muhs, A.** and C.L. Quave. (2017). Brazilian Peppertree: From noxious weed to a source of medicine? Food and Agriculture Organization of the United Nations (FAO) Non-wood Forest Product Update. Issue 11. [Link]
- Quave, C.L. (2016) Commentary on: “The adaptive nature of culture. A cross-cultural analysis of the returns of local environmental knowledge in three indigenous societies” by V. Reyes-García, M. Guèze, I. Díaz-Reviriego, R. Duda, Á. Fernández-Llamazares, S. Gallois, L. Napitupulu, M. Orta-Martínez and A. Pyhälä. Current Anthropology 57(6):761-784.
- Quave, C.L., K. Barfield, N. Ross, and K.C. Hall (2015). Editorial: The Open Science Network in Ethnobiology: Growing the Influence of Ethnobiology. Ethnobiology Letters. 6:1-4. [Link]
- Pieroni, A., M. Pardo-de-Santayana, F. Firenzuoli, and C.L. Quave. (2013). Editorial: The European Heritage of Folk Medicines and Medicinal Foods: Its Contribution to the CAMs of Tomorrow. Evidence Based Complementary and Alternative Medicine. Volume 2013, Article ID 827521, http://dx.doi.org/10.1155/2013/827521 [Link]