Research Articles

Short Research Description

The Quave lab applies the ethnobotanical approach to drug discovery. We examine botanical natural products for anti-virulence activity in treatment of multidrug-resistant bacterial infections. This involves field research to document traditional therapies for skin infections, collection of plants for chemical extraction, and bioassay-guided fractionation strategies to isolate novel drugs. You can check the stats on our work in Google Scholar.

† Awards, honors, or high citations associated with the publication; ‡ Description of my contribution if I am neither first nor last author (per Emory guidelines); ** Students/postdocs/medical residents I have trained, undergraduate researchers are underlined; # Equal contributions.

Published and Accepted Research Articles in Peer Reviewed Journals:
  1. Khan, M.F.**, H. Tang**, J.T. Lyles, R. Pineau**, Z.R. Mashwani and C.L. Quave. (2018) Antibacterial properties of medicinal plants from Pakistan against multidrug-resistant ESKAPE pathogens. Frontiers in Pharmacology doi: 10.3389/fphar.2018.00815 [Link]
  2. Hajdari, A., A. Pieroni, M. Jhaveri**, B. Mustafa, C.L. Quave. (2018) Ethnomedical Knowledge of Slavic Speaking People in South Kosovo. Ethnobiology and Conservation 7:6. doi:10.15451/ec2018-03-07.06-1-42 [Link]
  3. Lyles, J.T.**#, Kim**#, K. Nelson, A. Bullard-Roberts**, A. Hajdari, B. Mustafa, C.L. Quave. (2017) The chemical and antibacterial evaluation of St. John’s Wort oil macerates used in Kosovar traditional medicine. Frontiers in Microbiology https://doi.org/10.3389/fmicb.2017.01639 [Link]
  4. Lavoie, S., D. Brumley, T.S. Alexander, C. Jasmin, F.A. Carranza, K. Nelson, C.L. Quave, and J. Kubanek. (2017) Iodinated meroditerpenes from a red alga Callophycus sp. The Journal of Organic Chemistry DOI: 10.1021/acs.joc.7b00096 [Link]
    1. ‡ Led antibacterial testing efforts for antibiotic potentiation assays reported in article.
  5. Lyles, J.T.**, Tyler**, E.J. Bradbury, K. Nelson, C.F. Brown, S.T. Pierce, C.L. Quave (2017). Comparative Phytochemical Analysis of Schisandra spp. (Chinese and Bay Starvine) Journal of Dietary Supplements 1-13. doi: 10.1080/19390211.2017.1304483 [Link]
  6. Fontaine, B.M., K. Nelson, J.T. Lyles**, B. Jariwala**, J. M. Garcia-Rodriguez, C.L. Quave#, E.E. Weinert#. (2017) Identification of ellagic acid rhamnoside as a bioactive component of a complex botanical extract. Frontiers in Microbiology 8:496 doi: 10.3389/fmicb.2017.00496 [Link]
  7. Muhs, A.**, J.T. Lyles**, C.P. Parlet, K. Nelson, J.S. Kavanaugh, A. R. Horswill, C.L. Quave. (2017) Virulence inhibitors from Brazilian Peppertree block quorum sensing and abate dermonecrosis in skin infection models. Scientific Reports 7: 42275 doi:10.1038/srep42275 [Link]
  8. Pieroni, A. R. Sõukand, C.L. Quave, A. Hajdari and B. Mustafa. (2017) Traditional food uses of wild plants among the Gorani of South Kosovo. Appetite 108:83-92.DOI 10.1016/j.appet.2016.09.024 [Link]
    1. ‡ Contributed to field research, data analysis and revising the article.
  9. Quave, C.L. and A. Saitta. (2016) Forty-five years later: The shifting dynamic of traditional ecological knowledge Pantelleria Island, Italy. Economic Botany 70(4): 380-393. doi:10.1007/s12231-016-9363-x [Link]
    1. † Article photo selected for journal cover art.
  10. Nelson, K., J.T. Lyles, Li**, A. Saitta, E. Addie-Noye**, P. Tyler**, C. L. Quave. (2016) Anti-acne activity of Italian medicinal plants used for skin infection. Frontiers in Pharmacology 7:425 http://dx.doi.org/10.3389/fphar.2016.00425 [Link]
  11. Hajdari, A., B. Mustafa, D. Nebija, H. Selimi, Z. Veselaj, P. Breznica, C.L. Quave and J. Novak. (2016). Essential oil composition of Pinus peuce Griseb. needles and twigs from two national parks of Kosovo. The Scientific World Journal http://dx.doi.org/10.1155/2016/5393079 [Link]
    1. ‡ Contributed to chemistry aims, data analysis and revising the article.
  12. Pulaj, B.**, B. Mustafa, K. Nelson, C.L. Quave, A. Hajdari. (2016) Chemical composition and in vitro antibacterial activity of Pistacia terebinthus essential oils derived from wild populations in Kosovo. BMC Complementary and Alternative Medicine 16:147. DOI 10.1186/s12906-016-1135-8 [Link]
    1. ‡ Contributed to chemistry aims, data analysis and revising the article.
  13. Hajdari, A., B. Mustafa, G. Ahmeti, B. Pulaj**, B. Lukas, A. Ibraliu, G. Stefkov, C.L. Quave, J. Novak. (2015). Essential oil variation among natural populations of Pinus mugo Turra in Kosovo. SpringerPlus 4:828 DOI 10.
    1. ‡ Contributed to chemistry aims, data analysis and revising the article. [Link]
  14. Hadjari, A., B. Mustafa, D. Nebija, E. Miftari, C.L. Quave, J. Novak. (2015) Chemical composition of Juniperus communis L. cone essential oil and its variability among wild populations in Kosovo. Chemistry and Biodiversity, 12: 1706–1717. doi: 10.1002/cbdv.201400439 [Link]
    1. ‡ Contributed to chemistry aims, data analysis and revising the article.
  15. Quave, C.L., J.T. Lyles**, J.S. Kavanaugh, K. Nelson, C.P. Parlet, H.A. Crosby, K.P. Heilmann, A.R. Horswill. (2015) Castanea sativa (European Chestnut) leaf extracts rich in ursene and oleanene derivatives block Staphylococcus aureus virulence and pathogenesis without detectable resistance. PLoS ONE 10(8): e0136486. doi:10.1371/journal.pone.0136486 [Link]
    1. † Article selected as Editor’s Pick in PLoS ONE Collection on Microbiology (http://collections.plos.org/microbiology-picks)
  16. Sõukand, R., M. Biró, A. Dénes,Y. Doğan, A. Hajdari, R. Kalle, B. Reade, B. Mustafa, A. Nedelcheva, C.L. Quave, Ł. Łuczaj, A. Pieroni. (2015) An ethnobotanical perspective on traditional fermented plant foods and beverages in Eastern Europe. Journal of Ethnopharmacology. 170:284-296. [Link]
    1. ‡ Contributed to field research aims, data analysis and revising the article.
  17. Mustafa, B., A. Hajdari, A. Pieroni, B. Pulaj**, C. Koro, C.L. Quave. (2015) A cross-cultural comparison of folk plant uses among Albanians, Bosniaks, Gorani, and Turks living in southwest Kosovo. Journal of Ethnobiology and Ethnomedicine. 11:39. doi:10.1186/s13002-015-0023-5 [Link]
  18. Bartha, S.G., L. Quave, L. Balogh, N. Papp. (2015) Ethnoveterinary practices of Covasna County, Transylvania, Romania. Journal of Ethnobiology and Ethnomedicine. 11:35. doi:10.1038/518487a [Link]
    1. ‡ Contributed to field research aims, data analysis and revising the article.
  19. Quave, C.L. and A. Pieroni. (2015). A reservoir of ethnobotanical knowledge informs resilient food security and health strategies in the Balkans. Nature Plants DOI: 10.1038/NPLANTS.2014.21 [Link]
    1. † Editorial (mentions above article): Surridge, C. 2015. Plant science’s human factor. Nature Plants DOI: 10.1038/NPLANTS.2015.13 [Link]
    2. † News and Views Commentary (focuses on article): Pardo-de-Santayana, M. and M. Macia. 2015. Biodiversity: The benefits of traditional knowledge. Nature 518: 487-488. doi:10.1038/518487a [Link]
    3. † Web of Science notation: As of November/December 2017, this highly cited paper received enough citations to place it in the top 1% of the academic field of Plant & Animal Science based on a highly cited threshold for the field and publication year.
  20. Papp, N., D. Czégényi, A. Hegedűs, T. Morschhauser, C.L. Quave, K. Cianfaglione and A. Pieroni (2014). The uses of Betula pendula Roth among Hungarian Csángós and Székelys in Transylvania, Romania. Acta Societatis Botanicorum Poloniae 83(2): 113-122. [Link]
    1. ‡ Contributed to data analysis and revising the article.
  21. Talekar, S.J., S. Chochua, K. Nelson, K.P. Klugman, C.L. Quave and J.E. Vidal (2014). 220D-F2 from Rubus ulmifolius kills Streptococcus pneumoniae planktonic cells and pneumococcal biofilms. PLoS ONE 9(5): e97314. [Link]
    1. ‡ Led chemistry aims, contributed to data analysis and study design, and revising the article.
  22. Pieroni, A., K. Cianfaglione, A. Nedelcheva, A. Hajdari, B. Mustafa and C.L. Quave (2014). Resilience at the border: traditional botanical knowledge among Macedonians and Albanians living in Gollobordo, Eastern Albania. Journal of Ethnobiology and Ethnomedicine 10:31. [Link]
  23. Quave, C.L. and A. Pieroni (2014) Fermented foods for food sovereignty and food security in the Balkans: A case study of the Gorani people of northeastern Albania. Journal of Ethnobiology 34(1): 28-43. [Link]
  24. Abbasi, A.M., S.M. Khan, M. Ahmad, M.A. Khan, C.L. Quave, and A. Pieroni. (2014). Botanical ethnoveterinary therapies in three districts of the Lesser Himalayas of Pakistan. Journal of Ethnobiology and Ethnomedicine. 9:84. [Link]
    1. ‡ Contributed to field research data analysis and revising the article.
  25. Pieroni, A., A. Nedelcheva, A. Hadjari, B. Mustafa, B. Scaltriti, K. Cianfaglione, and C. L. Quave. (2014). Local knowledge on plants and domestic remedies in the mountain villages of Peshkopia (Eastern Albania). Journal of Mountain Science 11(1): 180-194. [Link]
  26. Jiang, S.** and C.L. Quave. (2013). A comparison of traditional food and health strategies among Taiwanese and Chinese immigrants in Atlanta, Georgia, USA. Journal of Ethnobiology and Ethnomedicine 9:61. [Link]
  27. Pieroni, A., B. Rexhepi, A. Nedelcheva, A. Hajdari, B. Mustafa, V. Kolosova, K. Cianfaglione, and C.L. Quave. (2013) One century later: the folk botanical knowledge of the last remaining Albanians of the upper Reka Valley, Mount Korab, Western Macedonia. Journal of Ethnobiology and Ethnomedicine. 9:22. [Link]
  28. Rexhepi, B., B. Mustafa, A. Hajdari, J. Rushidi-Rexhepi, C.L. Quave and A. Pieroni. (2013). Traditional medicinal plant knowledge among Albanians, Macedonians and Gorani in the Sharr Mountains (Republic of Macedonia). Genetic Resources and Crop Evolution DOI 10.1007/s10722-013-9974-3 [Link]
    1. ‡ Contributed to field research, data analysis, and revising the article.
  29. Mattalia, G., C.L. Quave, and A. Pieroni (2013) Traditional uses of wild food and medicinal plants among Brigasc, Kyé, and Provençal communities on the Western Italian Alps. Genetic Resources and Crop Evolution. 60:587-603. [Link]
    1. ‡ Contributed to analysis of field research data and revising the article.
  30. Hobby, G.**, C. L. Quave, K. Nelson, C. Compadre, K. Beenken, and M.S. Smeltzer. (2012) Quercus cerris extracts limit Staphylococcus aureus biofilm formation. Journal of Ethnopharmacology. 144(3): 812-815. [Link]
    1. ‡ Led the chemical analysis aims and supervised microbiological assays, contributed to data analysis and revising the article. Listed as corresponding author.
  31. Ellena, R., C.L. Quave and A. Pieroni (2012) Comparative medical ethnobotany of the Senegalese community living in Turin (North-Western Italy) and in Adeane (Southern Senegal). Evidence-Based Complementary and Alternative Medicine. doi:10.1155/2012/604363 [Link]
    1. ‡ Contributed to analysis of field research data and revising the article.
  32. Pieroni, A., C.L. Quave and M.E. Giusti. (2012) “We are Italians!”: the hybrid ethnobotany of a Venetian diaspora in Eastern Romania. Human Ecology. doi: 10.1007/s10745-012-9493-4 [Link]
    1. ‡ Contributed to analysis of field research data and revising the article.
  33. di Tizio, A., Ł. Łuczaj, C.L. Quave, S. Redžić and A. Pieroni (2012). Traditional food and herbal uses of wild plants in the ancient South-Slavic diaspora of Mundimitar/Montemitro (Southern Italy). Journal of Ethnobiology and Ethnomedicine. 8:21 [Link]
    1. ‡ Contributed to analysis of field research data and revising the article.
  34. Mustafa, B. A. Hajdari, F. Krasniqi, E. Hoxha, H. Ademi, C.L. Quave and A. Pieroni (2012). Medical ethnobotany of the Albanian Alps in Kosovo. Journal of Ethnobiology and Ethnomedicine. 8:6. [Link]
    1. ‡ Contributed to field research, data analysis, and revising the article.
  35. Quave, C.L., M.E. Carmona, C.M. Compadre, G. Hobby**, H. Hendrickson, K. Beenken, and M.S. Smeltzer. (2012). Ellagic acid derivatives from Rubus ulmifolius inhibit Staphylococcus aureus biofilm formation and improve response to antibiotics. PLoS ONE 7(1): e28737. [Link]
  36. Mustafa, B., A. Hajdari, Q. Pajazita, B. Syla, C.L. Quave, and A. Pieroni (2011). An ethnobotanical survey of the Gollak region, Kosovo. Genetic Resources and Crop Evolution. doi: 10.1007/s10722-011-9715-4 [Link]
    1. ‡ Contributed to analysis of field research data and revising the article.
  37. Ordóñez, P.E., C. L. Quave, W.F. Reynolds, K.I. Varughese, B. Berry, O. Malagón, M.S. Smeltzer, and C.M. Compadre. (2011). Sesquiterpene lactones of Gynoxys verrucosa and their anti-MRSA activity. Journal of Ethnopharmacology 137(2):1055-1059. [Link]
    1. ‡ Led antibacterial assays, contributed to data analysis and revision of the article.
  38. Pieroni, A., M.E. Guisti, and C.L. Quave. (2011) Cross-cultural ethnobiology in the Western Balkans: medical ethnobotany and ethnozoology among Albanians and Serbs in the Pešter plateau, Sandžak, south-western Serbia. Human Ecology 39: 333-349. [Link]
  39. Quave, C.L., L.R.W. Plano, and B.C. Bennett (2010) Quorum sensing inhibitors for Staphylococcus aureus from Italian medicinal plants. Planta Medica, 76: 1-8. [Link]
  40. Quave, C.L., U. Lohani, A. Verde, J. Fajardo, D. Rivera, C. Obón, A. Valdes, and A. Pieroni (2010). A comparative assessment of zootherapeutic remedies from selected areas in Albania, Italy, Spain and Nepal. Journal of Ethnobiology 30(1): 92-125. [Link]
  41. Bhattarai, S., R.P. Chaudhary, C.L. Quave, and R.S.L. Taylor. (2010). The use of medicinal plants in the trans-himalyan arid zone of Mustang district, Nepal. Journal of Ethnobiology and Ethnomedicine 6:14. [Link]
    1. ‡ Contributed to analysis of field research data and revising the article.
  42. Quave, C.L., L.R.W. Plano, T. Pantuso, and B.C. Bennett (2008). Effects of extracts from Italian medicinal plants on planktonic growth, biofilm formation and adherence in MRSA. Journal of Ethnopharmacology 118: 418-428. [Link]
    1. † Cited in literature >200 times.
  43. Quave, C.L., A. Pieroni, and B.C. Bennett (2008) Dermatological remedies in the traditional pharmacopoeia of Vulture-Alto Bradano, inland southern Italy. Journal of Ethnobiology and Ethnomedicine 4:5. [Link]
  44. Pieroni, A. and C.L. Quave. (2005). Traditional pharmacopoeias and medicines among Albanians and Italians in southern Italy: A comparison. Journal of Ethnopharmacology 101(1-3): 258-270. [Link]
    1. † Cited in literature >150 times.
  45. Quave, C.L. and A. Pieroni. (2005). Ritual healing in Arbëreshë Albanian and Italian communities of Lucania, southern Italy. Journal of Folklore Research 42(1): 57-97. [Link]
  46. Pieroni, A., C.L. Quave and R.F. Santoro. (2004). Folk pharmaceutical knowledge in the territory of the Dolomiti Lucane, inland southern Italy. Journal of Ethnopharmacology 95(2-3): 373-384. [Link]
    1. † Cited in literature >150 times.
    2. ‡ Contributed to field research, data analysis, and revising the article.
  47. Pieroni, A., C.L. Quave, M.L.Villanelli, P. Mangino, G. Sabbatini, L. Santini, T. Boccetti, M. Profili, T. Ciccioli, L.G. Rampa, G. Antonimi, C. Girolamini, M. Cecchi, and M.Tomasi. (2004). Ethnopharmacognostic survey on the natural ingredients used in folk cosmetics, cosmeceuticals and remedies for healing skin diseases in the inland Marches, Central-Eastern Italy. Journal of Ethnopharmacology 91: 331-344. [Link]
    1. † Cited in literature >100 times.
    2. ‡ Contributed to analysis of field research data and revising the article.
  48. Pieroni, A., C. Quave, S. Nebel and M. Heinrich. (2002). Ethnopharmacy of the ethnic Albanians (Arbëreshë) in northern Basilicata, Italy. Fitoterapia 73: 217-41. [Link]
    1. † Cited in literature >100 times.
  49. Pieroni, A., S. Nebel, C. Quave and M. Heinrich. (2002). Ethnopharmacology of liakra: traditional weedy vegetables of the Arbëreshë of the Vulture area in southern Italy. Journal of Ethnopharmacology 81: 165-85. [Link]
    1. † Cited in literature >200 times.
    2. ‡ Contributed to field research, data analysis, and revising the article.
  50. Quave, C.L. (1999). Helminthic infection and anemia in childhood: A comparative analysis of Western and traditional medicine in Tamanco Jurisdiction, Napo River, Amazon. Lambda Alpha Journal 29: 29-39. [Link]
Be Sociable, Share!

Comments are closed