New book chapter: Antibiotics from nature

Dr. Quave has published a chapter in the new volume by the World Alliance Against Antibiotic Resistance:

Quave, C.L. Antibiotics from nature: Traditional medicine as a source of new solutions for combating antimicrobial resistance. AMR Control 2016: Overcoming Global Antimicrobial Resistance. World Alliance Against Antibiotic Resistance


Plants have served as a valuable source of ingredients for traditional medicines for millennia. Historical records and modern ethnobotanical field studies highlight their importance in the traditional treatment of infectious disease. However, plants make up only a tiny percentage of the current repertoire of FDA-approved antibacterial drugs. This article provides an overview of the benefits and challenges of exploring plants as a new source of antimicrobials to use in the fight against multidrug-resistant bacteria. It also reviews the ethnobotanical approach to drug discovery and discusses a number of innovative targets for future drug discovery efforts in this field.