A new publication is out on a collaborative project between the Quave Lab (Emory University) and Horswill Lab (University of Iowa). Their latest study reports on the anti-virulence activity of compounds from Chestnut leaves. The extract blocks virulence by switching off the pathways necessary for the production of toxins. The paper is available via Open Access here: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0136486

Castanea sativa (European Chestnut) Leaf Extracts Rich in Ursene and Oleanene Derivatives Block Staphylococcus aureus Virulence and Pathogenesis without Detectable Resistance

• Cassandra L. Quave ,
• James T. Lyles,
• Jeffery S. Kavanaugh,
• Kate Nelson,
• Corey P. Parlet,
• Heidi A. Crosby,
• Kristopher P. Heilmann,
• Alexander R. Horswill